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Amyotrophic Lateral Sclerosis and Riluzole: How the First FDA-Approved Drug Slows ALS Progression
Martin Kelly 17 February 2026 12

Amyotrophic Lateral Sclerosis and Riluzole: How the First FDA-Approved Drug Slows ALS Progression

Riluzole is the first FDA-approved drug for ALS, modestly extending survival by 2-3 months. It works by reducing toxic glutamate activity in motor neurons. Despite side effects and limited efficacy, it remains the most prescribed ALS treatment worldwide.

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