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Tag: chronic opioid therapy

Opioids and Adrenal Insufficiency: A Rare but Life-Threatening Side Effect You Need to Know
Martin Kelly 19 November 2025 0

Opioids and Adrenal Insufficiency: A Rare but Life-Threatening Side Effect You Need to Know

Opioid-induced adrenal insufficiency is a rare but life-threatening side effect of long-term opioid use. It suppresses stress hormones, mimics fatigue, and can cause fatal crashes during illness. Screening with an ACTH test can save lives.

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