Acne medication: what works and how to use it

Dealing with acne? You want something that actually works and won’t cause surprises. This page breaks down the main acne medicines, how they help, common side effects, and smart tips for buying prescriptions safely—especially online.

Common acne meds and what they do

Topical retinoids (tretinoin, adapalene) unclog pores and speed skin cell turnover. Use them at night, expect irritation for the first 2–4 weeks, and always wear sunscreen. Benzoyl peroxide kills acne bacteria and reduces inflammation; it can bleach towels and pillowcases, so watch what it touches. Combine benzoyl peroxide with a topical antibiotic sometimes, but only short-term to avoid resistance.

Oral antibiotics like doxycycline or minocycline are used for moderate inflammatory acne. They reduce bacteria and calm inflammation but aren’t meant for long-term use because of resistance and side effects like sun sensitivity or stomach upset. If antibiotics are needed for more than a few months, your doctor should plan a follow-up and consider stepping down to topical maintenance.

Isotretinoin (branded forms like Ssotroin) is the strongest tool for severe or scarring acne. It often clears acne when nothing else works, but side effects are real: very dry skin, chapped lips, changes in blood lipids and liver tests, and strong birth-defect risk if used by pregnant people. Labs and regular check-ins with a prescriber are standard. Men also need monitoring—liver enzymes and lipids should be checked before and during treatment.

How to choose and buy acne drugs safely

Start with a professional diagnosis. Acne can look similar to rosacea or folliculitis, and treatment differs. Ask a dermatologist or a trusted prescriber for a plan—topicals first for mild cases, oral options for moderate cases, and isotretinoin for severe or scarring acne.

If you’re buying online, be picky. Choose pharmacies that require a prescription, show clear contact info, list a licensed pharmacist, and display verifiable business details. Avoid sites that sell isotretinoin or other prescription drugs with no prescription or a one-question quiz. Read independent reviews and compare prices—very cheap is often a red flag. If a site promises no monitoring for isotretinoin, walk away.

When starting any acne drug, keep a simple record: start date, dose, side effects, and follow-up dates. Use gentle cleansers, moisturizers, and daily sunscreen to reduce irritation. If side effects become worse or you notice mood changes, severe headaches, or unexplained symptoms, contact your provider immediately.

Want deeper info? Check our detailed guides on isotretinoin, how to order prescription meds online, and reviews of online pharmacies. They walk you through prescriptions, lab checks, and trusted buying tips so you can treat acne safely and confidently.